ISSN 1308-8734 | E-ISSN 1308-8742
Review
Helicobacter Pylori in Otorhinolaryngology: Cause or Bystander
1 Department of Otorhinolaryngology, University Hospital Mostar, Mostar, Bosnia and Herzegovina; University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina  
2 Department of Pathology, Cytology and Forensic Medicine, University Hospital Mostar, Mostar, Bosnia and Herzegovina; University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina  
3 Department of Oncology, University Hospital Mostar, Mostar, Bosnia and Herzegovina; University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina  
4 Department of Gastroenterology, University Hospital Mostar, Mostar, Bosnia and Herzegovina; University of Mostar School of Medicine, Mostar, Bosnia and Herzegovina  
Eurasian J Med ; : -
DOI: 10.5152/eurasianjmed.2018.18192
Key Words: Helicobacter pylori, otorhinolaryngology, laryngopharyngeal reflux, nasopharyngeal reflux
Abstract

 

The bacteria Helicobacter pylori (H. pylori) have been identified in extragastric tissues  in the head and neck. The origin and pathogenicity of these bacteria in the head and neck are not known. The possible modes of spread are gastric reflux, a nasal or oral route. Laryngopharyngeal reflux has been identified as a contributing or causative factor in many sinonasal, pharyngeal, laryngeal and middle ear disorders. One of the possible modes by which laryngopharyngeal reflux may contribute is by seeding of the extragastric mucosa with H. pylori. The clinical significance of the discovery of H. pylori in extragastric tissues  in the head and neck is unclear. There is no evidence of a pathologic or active role of H. pylori in otorhinolaryngological disorders. The suggestion that sinonasal cavities and pharynx may serve as a reservoir for H. pylori and that re-infection of the stomach occurs after eradication therapy awaits further studies for confirmation. No connection between H. pylori in the stomach and H. pylori, found in the head and neck, was proved. Also, these bacteria, found in the head and neck tissues, may be accidental or innocent bystanders which do not affect the pathways of otolaryngological and gastroduodenal diseases. This review examines the evidence for a possible relationship of H. pylori with otorhinolaryngological diseases.

 

 

Cite this article as:  Jelavic B, Petricevic J, Marijanović I, Bevanda M. Helicobacter Pylori in Otorhinolaryngology: Cause or Bystander. Eurasian J Med 2018; DOI: 10.5152/eurasianjmed.2018.18192

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