ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
RELATIONSHIP OF THE DISEASE ACTIVITY BETWEEN FERRITIN LEVELS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
1 Atatürk Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı Erzurum  
2 Atatürk Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı, Erzurum  
3 Atatürk Üniversitesi Tıp Fakültesi Nefroloji Bilim Dalı, Erzurum  
Eurasian J Med 2001; 33: 79-82

Key Words: SLE, Acute phase reactant, Ferritin
Abstract

Ferritin is an acute phase reactant which indicates serum ıron storage. Its serum levels increase 10 to 100 folds responding to inflammatory stimulation. In parallel to decreasing of active of disease, levels of ferritin decrease. To investigate the relationship between serum ferritin and disease activity in systemic lupus erythematosus (SLE), we enrolled 20 patients with SLE (16 female, 4 males and mean ages: 26.6  7.8 (14-45) years). The serum ferritin levels were detected in active period and remission period by treatment of disease in-patients with SLE. The serum ferritin levels were 1097.8  382.8 (345-1800) ng/ml and 214.5  71.1 (114-345) ng/ml in active period and remission period by treatment, respectively. The ferritin levels were low that were meaningful statistically, in active period of disease comparing with remission period. In management of patients with SLE, the measurements of serum ferritin levels should be made routinely, because of the test are easy, economic, safe and guide of management.

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