ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
ALBUMIN METABOLISM IN NEPHROTIC SYNDROME
1 Atatürk Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Erzurum  
Eurasian J Med 2002; 34: 51-53

Key Words: Nephrotic syndrome, Albumin metabolism
Abstract

Hypoalbüminemia is one of the hallmarks of the nephrotic syndrome. In nephrotic patients the primary causes of hypoalbuminemia are urinary albumin losses, an inappropriate increase in the fractional catabolic rate of albumin and an insufficient increase in the rate of albumin synthesis to replace these losses. There is no evidence that shifts of albumin to the extra vascular space or that dilution of plasma by volume expansion play any role in causing hypoalbuminemia in nephrotic patients.

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