ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
The Effects of Metabolic Syndrome on TpTe Interval and TpTe/QT Ratio in Patients with Normal Coronary Arteries
1 Clinic of Cardiology, Bursa Training and Research Hospital, Bursa, Turkey  
2 Clinic of Cardiology, Bursa Sevket Yilmaz Training and Research Hospital, Bursa, Turkey  
Eurasian J Med 2014; 46: 182-186
DOI: 10.5152/eajm.2014.48
Key Words: TpTe/QT ratio, arrhytmia, metabolic syndrome

Objective: T wave peak to T wave end (TpTe) interval and TpTe/QT have been accepted as predictors of ventricular arrythmia. In this study our aim is to investigate the effect of metabolic syndome on these parameters in patients with angiographically normal coronary arteries.


Materials and Methods: Thirty patients with metabolic syndrome (4 male, mean age 52±7.8 years) and twenty patients without metabolic syndrome as control group (8 male, mean age 54±9.3 years) were included. TpTe interval and TpTe/QT ratio were measured from the 12-lead electrocardiogram. These parameters were compared between the groups


Results: When compared with to the control group the systolic and diastolic blood pressure, pulse pressure, waist circumference, triglyceride and fasting plasma glucose levels were higher and HDL cholesterol level was lower in the metabolic syndrome group. In the analysis of electrocardiography, QT dispersion (QTd) and corrected QTd were significantly increased in metabolic syndrome group as compared to the controls group (44±14 versus 30±12 ms and 433±10 versus 405±4 ms, all p value p=0.01). TpTe interval and TpTe/QT ratio were also significantly higher in patient with metabolic syndrome (112±10 versus 91±10 ms and 0.25±0.02 versus 0.22±0.01, all p value p=0.01).


Conclusion: According to these results, we supposed that TpTe/QT ratio and TpTe interval is prolonged and those patients with metabolic syndrome may be at greater risk of ventricular arrhythmias. 

Key Words
Author’s Corner
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