ISSN 1308-8734 | E-ISSN 1308-8742
Review
Growth Hormone Therapy in Children with Chronic Renal Failure
1 Department of Pediatric Endocrinology, Regional Training and Research Hospital, Erzurum, Turkey  
2 Department of Pediatric Nephrology, Ataturk University Faculty of Medicine, Erzurum, Turkey  
Eurasian J Med 2015; 47: 62-65
DOI: 10.5152/eajm.2014.57
Key Words: Child, chronic renal failure, growth hormone, therapy
Abstract

Growth is impaired in a chronic renal failure. Anemia, acidosis, reduced intake of calories and protein, decreased synthesis of vitamin D and increased parathyroid hormone levels, hyperphosphatemia, renal osteodystrophy and changes in growth hormone-insulin-like growth factor and the gonadotropin-gonadal axis are implicated in this study. Growth is adversely affected by immunosuppressives and corticosteroids after kidney transplantation. Treating metabolic disorders using the recombinant human growth hormone is an effective option for patients with inadequate growth rates.

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