ISSN 1308-8734 | E-ISSN 1308-8742
Case Report
Metastatic Chordoma: Report of the Two Cases and Review of the Literature
1 Brigham and Women's Hospital/Dana Farber Cancer institute/ Harvard Medical School - Radiology Boston, Massachusetts, USA  
Eurasian J Med 2015; 47: 151-154
DOI: 10.5152/eurasianjmed.2015.52
Key Words: Chordoma, metastasis, imatinib, positron emission tomography

Chordomas are rare malignant bone tumours with a predilection for the axial skeleton, especially the sacrum and skull base. Median survival in patients with metastatic disease is usually dismal. Treatment is challenging due to the propensity for local recurrence, metastatic disease as well as lack of clear consensus regarding the optimal management. Our case report highlights two cases of sacral chordoma with locally recurrent and widespread metastatic disease, stable on molecular targeted therapy.

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