ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
Pediatric Liver Transplantation: Our Experiences
1 Department of Pediatric Gastroenterology, Akdeniz University School of Medicine, Antalya, Turkey  
2 Clinic of Pediatrics, Konya Training and Research Hospital, Konya, Turkey  
3 Department of General Surgery, İstanbul Yeni Yüzyil University School of Medicine, İstanbul, Turkey  
4 Department of General Surgery, Akdeniz University School of Medicine, Antalya, Turkey  
Eurasian J Med 2016; 48: 209-212
DOI: 10.5152/eurasianjmed.2016.0147
Key Words: Child, liver transplantation, liver failure
Abstract

Objective: The aim of our study was to evaluate our liver transplant pediatric patients and to report our experience in the complications and the long-term follow-up results.

 

Materials and Methods: Patients between the ages of 0 and 18 years, who had liver transplantation in the organ transplantation center of our university hospital between 1997 and 2016, were included in the study. The age, sex, indications for the liver transplantation, complications after the transplantation, and long-term follow-up findings were retrospectively evaluated. The obtained results were analyzed with statistical methods.

 

Results: In our organ transplantation center, 62 pediatric liver transplantations were carried out since 1997. The mean age of our patients was 7.3 years (6.5 months–17 years). The 4 most common reasons for liver transplantation were: Wilsons disease (n=10; 16.3%), biliary atresia (n=9; 14.5%), progressive familial intrahepatic cholestasis (n=8; 12.9%), and cryptogenic cirrhosis (n=7; 11.3%). The mortality rate after transplantation was 19.6% (12 of the total 62 patients). The observed acute and chronic rejection rates were 34% and 4.9%, respectively. Thrombosis (9.6%) was observed in the hepatic artery (4.8%) and portal vein (4.8%). Bile leakage and biliary stricture rates were 31% and 11%, respectively. 1-year and 5-year survival rates of our patients were 87% and 84%, respectively.

 

Conclusion: The morbidity and mortality rates in our organ transplantation center, regarding pediatric liver transplantations, are consistent with the literature.

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