ISSN 1308-8734 | E-ISSN 1308-8742
Review
Thymectomy in Myasthenia Gravis
1 Department of Thoracic Surgery, Atatürk University School of Medicine, Erzurum, Turkey.  
2 Department of Thoracic Surgery, Kırklareli State Hospital, Kırklareli, Turkey  
3 Department of Otorhinolaryngology, Atatürk University School of Medicine, Erzurum, Turkey  
4 Department of Cardiovascular Surgery, Atatürk University School of Medicine, Erzurum, Turkey  
Eurasian J Med 2017; 49: 48-52
DOI: 10.5152/eurasianjmed.2017.17009
Key Words: Extended thymectomy, follow-up, myasthenia gravis, thoracoscopic thymectomy
Abstract

In recent years, thymectomy has become a widespread procedure in the treatment of myasthenia gravis (MG). Likelihood of remission was highest in preoperative mild disease classification (Osserman classification 1, 2A). In absence of thymoma or hyperplasia, there was no relationship between age and gender in remission with thymectomy. In MG treatment, randomized trials that compare conservative treatment with thymectomy have started, recently. As with non-randomized trials, remission with thymectomy in MG treatment was better than conservative treatment with only medication. There are four major methods for the surgical approach: transcervical, minimally invasive, transsternal, and combined transcervical transsternal thymectomy. Transsternal approach with thymectomy is the accepted standard surgical approach for many years. In recent years, the incidence of thymectomy has been increasing with minimally invasive techniques using thoracoscopic and robotic methods. There are not any randomized, controlled studies which are comparing surgical techniques. However, when comparing non-randomized trials, it is seen that minimally invasive thymectomy approaches give similar results to more aggressive approaches.

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