ISSN 1308-8734 | E-ISSN 1308-8742
Case Report
Takayasu Arteritis Presenting as Renovascular Hypertension and Renal Failure in a Patient with Factor VII Deficiency
1 Department of Radiology, İstanbul Medeniyet University School of Medicine, İstanbul, Turkey  
2 Department of Cardiology, Istanbul Medeniyet University School of Medicine, İstanbul, Turkey  
Eurasian J Med 2018; 50: 210-212
DOI: 10.5152/eurasianjmed.2018.17324
Key Words: Takayasu arteritis, factor VII deficiency, renovascular hypertension, secondary hypertension, magnetic resonance angiography
Abstract

A 23-year-old female patient with factor VII (FVII) deficiency was admitted with severe hypertension and renal failure. Brachial arterial pressures were 230/120 and 220/115 mm/Hg on the right and left arms, respectively. There was no blood pressure difference between the arms. Renal artery Doppler ultrasonography revealed bilateral severe renal artery stenosis (RAS). Contrast-enhanced magnetic resonance imaging angiography (CE-MRA) revealed severe mural irregularities, contrast enhancement in the aorta and its branches, and long-segment stenosis starting in the abdominal aorta and extending into the proximal renal arteries. The diagnosis of Takayasu arteritis (TA) complicated by RAS in a patient with FVII deficiency was established. This is the first case of concomitant TA and factor VII deficiency in the literature. In conclusion, TA complicated with RAS should be kept in mind in the etiology of secondary hypertension, even when there is no blood pressure difference between the arms in patients. CE-MRA is an accurate, sensitive, and safe imaging method for diagnosing vasculitis, even in the early phases of the disease, and should be considered for evaluating the activity and response to treatment in patients with TA.

 

Cite this article as: Ozkok S, Aslan A, Gulseren Y, Kutlu Aciksari G, Agirbasli MA. A case report of factor VII deficiency and Takayasu Arteritis: the role of factor VII in maintaining vascular integrity. Eurasian J Med 2018; 50(3): 210-212.

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