ISSN 1308-8734 | E-ISSN 1308-8742
Original Article
Assessment of Endometrial Sampling and Histopathological Results: Analysis of 4,247 Cases
1 Department of Obstetrics and Gynecology, Konya Training and Research Hospital, Konya, Turkey  
2 Department of Pathology, Konya Training and Research Hospital, Konya, Turkey  
3 Department of Public Health, Necmettin Erbakan University School of Medicine, Konya, Turkey  
Eurasian J Med 2017; 49: 44-47
DOI: 10.5152/eurasianjmed.2017.16269
Key Words: Endometrial sampling, endometrial cancer, hysterectomy, histopathological examination

Objective: This study aimed to investigate the relationship between indications and histopathological results in patients undergoing endometrial sampling.


Materials and Methods: Data of 4,247 patients undergoing endometrial sampling due to non-obstetric gynecological causes between January 2010 and October 2016 were retrospectively evaluated using the archives of the Gynecology and Obstetrics Clinic of Konya Training and Research Hospital.


Results: The mean age of patients was 46.8 ± 8.22 years; the most common indication was menometrorrhagia/menorrhagia (70.66%), and the least common indication was cervical polyp (1.34%). The most common histopathological result was proliferative-secretory endometrium (63.62%); simple hyperplasia with atypia (0.56%) was determined to be the least common result. Endometrial cancer was observed more frequently in the post-menopausal bleeding and increased endometrial thickness group (23.11%). Of patients in whom biopsy was performed, 52.18% had undergone hysterectomy, as a result of which proliferative–secretory endometrium was most commonly (59.52%) and simple hyperplasia with atypia least commonly found as the histopathological diagnosis.


Conclusion: Although sampling should be performed following endometrial evaluation in patients with post-menopausal bleeding or increased endometrial thickness, according to the results of our study, routine endometrial biopsy should not be preferred in the other indications. 

Key Words
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