THE RELATIONSHIPS BETWEEN TROPONIN T MEASURED ON ADMISSION WITH THE SEVERITY OF CORONARY ATHEROSCLEROSIS AND LEFT VENTRICULAR WALL MOTIONS IN PATIENTS WITH NON-ST SEGMENT ELEVATION ACUTE CORONARY SYNDROMES

Abstract

In this study, we investigated the relationships between cardiac troponin T (TnT) measured on admission with the severity of angina, the severity of coronary atherosclerosis and left ventricular (LV) wall motions in patients with non-ST segment elevation acute coronary syndromes (ACS). 232 cases with unstable angina pectoris (Braunwald class I, II and III) performed coronary angiography before discharging included in this study. The cases were divided into two groups as high TnT (>0.1ng/ml, group 1) and normal TnT (≤ 0.1ng/ml, group 2). The severity of coronary atherosclerosis was evaluated according to Gensini score. Class I angina ratio was lower in group 1 than group 2 (p<0.0001). Class III angina ratio was higher in group 1 than group 2 (p<0.0001). According to Gensini score and abnormal LV wall motion, there were significant differences between two groups (p<0.05, p<0.001, respectively). In conclusion, this study shows that the relationships between TnT levels measured on admission with the severity of angina, severity of coronary atherosclerosis and abnormal LV wall motion were significant in patients with non-ST segment elevation ACS.